Ascorbic acid kills cancer

Ever had it before? Well you got it again.
robinson
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Ascorbic acid kills cancer

Post by robinson »

https://www.ncbi.nlm.nih.gov/pubmed/28108513/

Pauling knew ascorbic acid kills cancer cells (but not healthy cells). He used high concentrations by injecting it (eating it doesn't work the same). The octohats are pretty sure why now.

That high dose ascorbic also activates healthy cells to help protect them from radiation is also pretty damn cool. Somewhere somebody is doing research on this right now. I read a patent years ago (when this first came out) from some drug company, trying to patent giving high dose ascorobic acid and chemo at the same time.

I.V. ascorbic acid actually is a form of chemotherapy. It just doesn't make you sick.

Someday soon we are going to know, and see what the truth is.
The Atheist
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Re: Ascorbic acid kills cancer

Post by The Atheist »

Excellent spot - thanks.
Pyrrho
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Re: Ascorbic acid kills cancer

Post by Pyrrho »

*In mice and in vitro.
shemp
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Re: Ascorbic acid kills cancer

Post by shemp »

I can kill cancer cells in vitro with bleach. Doesn't make it a cure. Let's wait and see what happening with this in ten years.
Rob Lister
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Re: Ascorbic acid kills cancer

Post by Rob Lister »

Some promise
https://www.cancer.gov/about-cancer/tre ... amin-c-pdq
Bruce
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Re: Ascorbic acid kills cancer

Post by Bruce »

I eat ascorbic acid every day and I don't have cancer. Isn't that proof enough?

If word of this gets out, the anti-vax folks will call for a ban on oranges.
Witness
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Re: Ascorbic acid kills cancer

Post by Witness »

Pauling's late work on vitamin C has been largely criticized. You can read the details on his Wiki page: https://en.wikipedia.org/wiki/Linus_Pauling.

Where there's also this:
Eugenics

Pauling supported a limited form of eugenics by suggesting that human carriers of defective genes be given a compulsory visible mark - such as a forehead tattoo - to discourage potential mates with the same defect, in order to reduce the number of babies with diseases such as sickle cell anemia.
Doctor X
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Re: Ascorbic acid kills cancer

Post by Doctor X »

Linus Pauling died of?




Sorry to make you cry.

– J.D.
Pyrrho
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Re: Ascorbic acid kills cancer

Post by Pyrrho »

There are several clinical trials that are testing the use of ascorbic acid in the treatment of cancer, but none of them are examining the use of ascorbic acid alone.

https://www.cancer.gov/about-cancer/tre ... 0acid&rl=2
shemp
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Re: Ascorbic acid kills cancer

Post by shemp »

Doctor X wrote: Sat Feb 15, 2020 7:33 am Linus Pauling died of?




Sorry to make you cry.

– J.D.
He died from falling off a bar stool.
sparks
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Re: Ascorbic acid kills cancer

Post by sparks »

Cancer, if memory serves.
shemp
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Re: Ascorbic acid kills cancer

Post by shemp »

Didn't get enough vitamin C, no doubt.
Pyrrho
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Re: Ascorbic acid kills cancer

Post by Pyrrho »

Let's just say it wasn't scurvy.
Anaxagoras
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Re: Ascorbic acid kills cancer

Post by Anaxagoras »

Killing cancer cells has never been the problem. The problem is how to kill them without harming non-cancer cells.
shemp
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Re: Ascorbic acid kills cancer

Post by shemp »

Anaxagoras wrote: Sat Feb 15, 2020 10:56 pm Killing cancer cells has never been the problem. The problem is how to kill them without harming non-cancer cells.
Oh sure, you have to come in here and set limits? Killjoy!
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

Anaxagoras wrote: Sat Feb 15, 2020 10:56 pm Killing cancer cells has never been the problem. The problem is how to kill them without harming non-cancer cells.
Pretty much. Except even when you do kill cancer, it often returns.

https://medicine.yale.edu/news/yale-med ... ers-seeds/

Science is getting closer to actually understanding cancer
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

That the mechanism has been identified (just how ascorbic acid kills cancer cells), and it's interesting that capsaicin also kills cancer cells, by the same mechanism
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

Back in the day there was a lot of alternative therapy based on oxygen (which also kills cancer). Sadly the quacks were the only ones who tried it. The really smart octohats rejected this idea, because there was no mechanism to explain how it could work.
Doctor X
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Re: Ascorbic acid kills cancer

Post by Doctor X »

Needs more benzene.

– J.D.
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

In a new study, published recently in the December issue of the journal Redox Biology, Buettner and his colleagues have homed in on the biological details of how high-dose vitamin C (also known as ascorbate) kills cancer cells.

The study shows that vitamin C breaks down easily, generating hydrogen peroxide, a so-called reactive oxygen species that can damage tissue and DNA. The study also shows that tumor cells are much less capable of removing the damaging hydrogen peroxide than normal cells.

"In this paper we demonstrate that cancer cells are much less efficient in removing hydrogen peroxide than normal cells. Thus, cancer cells are much more prone to damage and death from a high amount of hydrogen peroxide," says Buettner, a professor of radiation oncology and a member of Holden Comprehensive Cancer Center at the University of Iowa. "This explains how the very, very high levels of vitamin C used in our clinical trials do not affect normal tissue, but can be damaging to tumor tissue."

Normal cells have several ways to remove hydrogen peroxide, keeping it at very low levels so it does not cause damage. The new study shows that an enzyme called catalase is the central route for removing hydrogen peroxide generated by decomposing vitamin C. The researchers discovered that cells with lower amounts of catalase activity were more susceptible to damage and death when they were exposed to high amounts of vitamin C.

Buettner says this fundamental information might help determine which cancers and which therapies could be improved by inclusion of high-dose ascorbate in the treatment.

"Our results suggest that cancers with low levels of catalase are likely to be the most responsive to high-dose vitamin C therapy, whereas cancers with relatively high levels of catalase may be the least responsive," he explains.

A future goal of the research is to develop methods to measure catalase levels in tumors.

https://www.sciencedaily.com/releases/2 ... 134014.htm
Doctor X
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Re: Ascorbic acid kills cancer

Post by Doctor X »

I am never sorry to make a Cunt cry, no.

– J.D.
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

https://visceralsynergy.com/assets/mito ... c-acid.pdf

Because AA kills cancer cells, how the fuck do cancer cells get AA? (even cancer cells require ascorbic acid to live)
We show here that human breast cancer tissues differentially express a form of SVCT2 transporter, that is systematically absent in normal breast tissues and it is increased in breast tumors. In fact, estrogen receptor negative breast cancer tissue, exhibit the most elevated SVCT2 expression levels. Despite this, our analysis in breast cancer cell lines showed that these cells are not able to uptake ascorbic acid and depend on glucose transporter for the acquisition of vitamin C by a bystander effect. This is consistent with our observations that this form of SVCT2 is completely absent from the plasma membrane and is overexpressed in mitochondria of breast cancer cells, where it mediates ascorbic acid transport. This work shows that breast cancer cells acquire vitamin C in its oxidized form and are capable of accumulated high concentrations of the reduced form.
https://www.sciencedirect.com/science/a ... 4919300450

Ah, sneaky motherfuckers.
robinson
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Re: Ascorbic acid kills cancer

Post by robinson »

robinson wrote: Tue Feb 18, 2020 11:35 am Normal cells have several ways to remove hydrogen peroxide, keeping it at very low levels so it does not cause damage. The new study shows that an enzyme called catalase is the central route for removing hydrogen peroxide generated by decomposing vitamin C. The researchers discovered that cells with lower amounts of catalase activity were more susceptible to damage and death when they were exposed to high amounts of vitamin C.

Buettner says this fundamental information might help determine which cancers and which therapies could be improved by inclusion of high-dose ascorbate in the treatment.

"Our results suggest that cancers with low levels of catalase are likely to be the most responsive to high-dose vitamin C therapy, whereas cancers with relatively high levels of catalase may be the least responsive," he explains.

A future goal of the research is to develop methods to measure catalase levels in tumors.

https://www.sciencedaily.com/releases/2 ... 134014.htm
Anaxagoras wrote: Sat Feb 15, 2020 10:56 pm Killing cancer cells has never been the problem. The problem is how to kill them without harming non-cancer cells.
A combination of AA and an engineered capsicum might be a novel way to attack cancer, without killing all cells. Between the hydrogen peroxide from AA and the apoptosis effects of capsaicin, (generation of reactive oxygen species, c-Jun N-terminal Kinase activation, mitochondrial depolarization, cytochrome c release in the cytosol, and caspase-3 cascade activation), combined with a little good old fashioned chemo....

well, who the fuck knows?

https://www.intechopen.com/chapters/71560

It might just as well kill you instead.