SARS-CoV-2 vaccines

[robinson]

The Amish and Sweden reached her immunity already

While Australia turned into Nazi Germany

[Anaxagoras]

For the time being, Japan seems to be headed in the right direction. Cases are down.

https://toyokeizai.net/sp/visual/tko/covid19/en.html

Of course, Japan was a latecomer to getting its population vaccinated (I'm still less than a month out from getting my second dose) so there has been less time for the immunity to wane.

[Pyrrho]

Current data from the CDC:

https://covid.cdc.gov/covid-data-tracke ... rate-total

Total Vaccine Doses
Delivered: 461,117,525
Administered: 382,294,795

"Administered" means actually injected into a person. 210,361,099 people have received at least one dose of a vaccine, so it's 7,653 deaths among that cohort, or 0.0036% incidence rate of death associated with the vaccination.

https://i.imgur.com/7civwjL.jpg

https://i.imgur.com/R5CapxA.png

VAERS data, although not as robust as data from controlled clinical trials in which adverse events are adjudicated as to whether or not they are caused by the study treatment, serve a valuable post-marketing purpose, not the least of which is to determine a "signal" of adverse event incidence rates. From the VAERS data, for example, there is a definite signal of higher incidence rate of death in the mRNA vaccines versus the viral vector vaccine.

One might consider comparing the incidence rates of severe illness and death in COVID-19 with the incidence rates of severe illness and death in the vaccines, in order to make an informed decision while consulting with their physician.

[robinson]

COVID-19 mRNA vaccines are given in the upper arm muscle. Once the instructions (mRNA) are inside the muscle cells, the cells use them to make the protein piece. After the protein piece is made, the cell breaks down the instructions and gets rid of them.

https://www.cdc.gov/coronavirus/2019-nc ... /mrna.html

the vector (not the virus that causes COVID-19, but a different, harmless virus) will enter a cell in our body and then use the cell’s machinery to produce a harmless piece of the virus that causes COVID-19. This piece is known as a spike protein and it is only found on the surface of the virus that causes COVID-19

.https://www.cdc.gov/coronavirus/2019-nc ... ector.html

You can tell how different they are. On causes your cells to make a spike protein, and the other uses your cells to make the spike protein.

[Anaxagoras]

Some recent UK data here (PDF):

Pages 5 and 6 are of particular interest:

https://assets.publishing.service.gov.u ... ation_.pdf

[Pyrrho]

COVID-19 mRNA vaccines are given in the upper arm muscle. Once the instructions (mRNA) are inside the muscle cells, the cells use them to make the protein piece. After the protein piece is made, the cell breaks down the instructions and gets rid of them.

https://www.cdc.gov/coronavirus/2019-nc ... /mrna.html

the vector (not the virus that causes COVID-19, but a different, harmless virus) will enter a cell in our body and then use the cell’s machinery to produce a harmless piece of the virus that causes COVID-19. This piece is known as a spike protein and it is only found on the surface of the virus that causes COVID-19

.https://www.cdc.gov/coronavirus/2019-nc ... ector.html

You can tell how different they are. On causes your cells to make a spike protein, and the other uses your cells to make the spike protein.

Two ways of saying the same thing.

BUT WHAT ABOUT THAT MACHINERY EPXLAIN THAT SPEKCTICS???!!!!

[robinson]

Two ways of saying the same thing.

Obviously. But two different vaccines

[Anaxagoras]

Just came across this one.

[robinson]

https://twitter.com/btysonmd/status/143 ... 91333?s=21

[robinson]

Looking at the world meter data there seems to be a summer spike in vaccinated countries

Wtf?

[Anaxagoras]

Japan has pretty much caught up to the US now in terms of vaccination rates, and new infections are dropping. The current state of emergency measures for Covid will be ended at the end of this month.

https://www.bloomberg.com/graphics/covi ... tribution/

https://toyokeizai.net/sp/visual/tko/covid19/en.html

https://english.kyodonews.net/news/2021 ... ource.html

[Anaxagoras]

Trials begin on Covid booster jab hoped to protect against new variants

[robinson]

I can remember when they mocked Trump because he said there would be vaccines


Because of how quickly a coronavirus mutates

[Pyrrho]

https://www.cell.com/cell-reports/fullt ... 21)01402-9

Here, we use structure-guided protein engineering to remove the S1 subunit from the Middle East respiratory syndrome (MERS)-CoV spike (S) glycoprotein and develop stabilized stem (SS) antigens. Vaccination with MERS SS elicits cross-reactive β-CoV antibody responses and protects mice against lethal MERS-CoV challenge.

[Hammerhead]

I can remember when they mocked Trump because he said there would be vaccines


Because of how quickly a coronavirus mutates

Trump says a lot of things that he has no evidence for. Scientists would never make that claim because no effective coronavirus vaccine had been produced before.

[Pyrrho]

https://www.npr.org/sections/coronaviru ... ffect-in-t

The U.S. Food and Drug Administration will need more time to decide whether to approve Moderna's COVID-19 vaccine for use in children ages 12 to 17, the company announced Sunday.

The extended timeline is so the FDA can look into reports of a rare side effect — myocarditis, or the inflammation of the heart muscle — in those who've gotten the shot. Moderna said the FDA informed the company of the delay on Friday.

[Pyrrho]

Twit: https://twitter.com/EricTopol/status/1524494556313448448

[robinson]

For the time being, Japan seems to be headed in the right direction. Cases are down.

https://toyokeizai.net/sp/visual/tko/covid19/en.html

Of course, Japan was a latecomer to getting its population vaccinated (I'm still less than a month out from getting my second dose) so there has been less time for the immunity to wane.

Japan,September 2021

17,00 deaths
23,000 new cases daily

Japan, September 2022

44,000 deaths
255,000 new cases a day

4 months later ...

Japan January 2023

66,000 deaths
245,000 new cases a day


Them mRNA treatments sure worked

[Pyrrho]

Executives where I work said that the pandemic is over, time to get everyone together in meetings! :hyper:

See? All we ever needed was in injection of corporate bossmanship.

[sparks]

Stupid fuckers. Good news is, they'll be at risk too.

[Pyrrho]

Eh, they're already touting ChatGPT as a new resource so it's only a matter of time before my next boss will be a bot.

[robinson]

Looking at the world data, the most vaccinated countries are having it way worse, like a magnitude worse, than poor unvaccinated countries.

[Pyrrho]

https://www.nejm.org/doi/full/10.1056/NEJMc2215471

Bivalent boosters provided substantial additional protection against severe omicron infection in persons who had previously been vaccinated or boosted, although the effectiveness waned over time. The effectiveness of bivalent boosters was higher than that of monovalent boosters.

[robinson]

It’s pretty amazing actually


Never before has there been a vaccine for a coronavirus, and here we have multiple ones, and a coronavirus that doesn’t mutate

It’s unbelievable

:De_Bunk: