The Covid vaccines really do work

[robinson]

If this sort of mRNA treatment worked as a vaccine, they would be doing animal research, especially for livestock. It would be a huge quantum fucking leap for protecting valuable animals from disease.

And we would have a fuck ton of real data about what does and does not work.

[Anaxagoras]

I'll just ignore that because the figure really speaks for itself.

[robinson]

When a promising new medical discovery looks promising, there is a lot of animal testing before using it on human children

[robinson]

Because, you know, bad shit might happen a ways down the line.

So the best practice is to test shit out first

Before injecting it into newborns

[Pyrrho]

https://www.medscape.com/viewarticle/967728

Novavax announced Monday that it has formally submitted a request to the FDA for emergency use authorization of its COVID-19 vaccine for ages 18 and older.

The request includes results from two large clinical trials that showed an overall efficacy of about 90% and a "reassuring safety profile," the company said.

"We believe our vaccine offers a differentiated option built on a well-understood protein-based vaccine platform that can be an alternative to the portfolio of available vaccines to help fight the COVID-19 pandemic," Stanley Erck, the president and CEO of Novavax, said in the statement.

[robinson]

https://twitter.com/drelidavid/status/1 ... 28363?s=21

[Anaxagoras]

Post hoc ergo propter hoc

Israel actually has fairly low vaccination rate. Lower even than the USA, which is pretty low, according to Our World in Data.

New cases is no longer a good metric for understanding what's going on. Nobody is saying that vaccination alone will prevent cases anymore. What it does do is prevent severe illness, hospitalization, and death.

Israel Finds Fourth COVID Booster is only ‘Partially Effective,’ Vast Majority of Hospitalised Omicron Patients Are Unvaccinated

A fourth COVID-19 booster mRNA vaccine has proven ineffective against Omicron infection, according to preliminary research from Israel released on Monday.

“Despite a significant increase in antibodies after the fourth vaccine, this protection is only partially effective against the Omicron strain, which is relatively resistant to the vaccine,” lead researcher Prof Gili Regev-Yochay, told a media briefing on Monday.

Some 154 health workers at Sheba Medical Center received their fourth Pfizer shot two weeks ago. A week ago, 120 healthworkers received a shot of Moderna following three doses of Pfizer one week ago.

They were matched with a control group of around 6,000 health workers who have been being followed by the hospital since the start of Israel’s vaccination campaign in December 2020.

According to Regev-Yochay, the third dose resulted in “much higher antibodies, neutralization and the antibodies were not just higher in quantity but also in quality” than the second dose – but the fourth vaccine did not show significant antibody increase.

”Maybe there are a few more antibodies but not much more compared to the third dose,” said Regev-Yochay.

Last week, she told Israeli Prime Minister Naftali Bennett that there had been a five-fold increase in antibodies in people who took the fourth dose, but she later told a radio station that “the amount of antibodies returns to the level it was after the third vaccine, not more. It’s nice, but it’s not what we expect from a booster.”

In addition, around the same percentage of hospital workers who received the fourth dose caught the virus as those who didn’t get the fourth booster.

Booster demand may affect global supply
Meanwhile, the European Medicines Agency (EMA) cautioned last week that there was no evidence to back a fourth booster, warning that repeat boosters every four months might actually weaken people’s immune systems.

Boosters “can be done once, or maybe twice, but it’s not something that we can think should be repeated constantly,” said Marco Cavaleri, the EMA head of biological health threats and vaccines strategy, said at a press briefing last week, as reported by Bloomberg.

Instead, the agency recommended that boosters should be tied to the cold season with longer intervals.

The World Health Organization (WHO) has also warned repeatedly against boosters while a high percentage of people in low and middle-income countries – estimated to be over 40% of the world’s population – are unvaccinated, fearing boosters will lower the number of vaccine doses available to these countries.

But, don't stop reading there:

Vast majority of Omicron patients in hospitals are unvaccinated
Meanwhile, the latest research from South Africa, New York City and California show that the vast majority of people hospitalised by the COVID-19 Omicron variant are unvaccinated – but that they still experienced less severe disease than those infected with Delta.

[Hotarubi]

Should I get a mop?

[Pyrrho]

https://twitter.com/KizzyPhD/status/1489697385962000385

[robinson]

Israel considers you unvaccinated if you haven’t had three shots

Those stats are bullshit

[robinson]

On June 20 2021 Israel had reached herd immunity, based on the number of people fully vaccinated

Most of the cases then were vaccinated people

Even more people are vaccinated now

The numbers of people with Covid make it clear the majority of people with Covid now are vaccinated

They are trying to deceive you

[post-skeptic]

The vaccines are ineffective and anyone saying different is a moron who believes what screens say over the obvious.

Never trust people that dumb again.

[Hotarubi]

Two mops?

[Doctor X]

Need Hazmat.

– J.D.

[Pyrrho]

https://www.nytimes.com/2022/02/09/heal ... cines.html

The Food and Drug Administration’s upcoming review of the Pfizer-BioNTech coronavirus vaccine for young children is without precedent in recent history.

Next week, scientific advisers to the agency will decide whether to endorse two doses of the vaccine for children 6 months through 4 years of age, before clinical trials have shown the full course — three doses — to be effective. Such an authorization would be a first for the agency, many experts say.

In fact, interim results from the trial suggested that two doses of the vaccine did not produce a strong immune response in children aged 2 through 4. Results from trials of the third dose are expected in a few weeks.

...

But the agency’s review of incomplete data as a basis for authorization has alarmed some experts.

“We’ve never done that before, that’s what gives me some pause,” said Dr. Gregory Poland, founder and director of the Mayo Vaccine Research Group in Minnesota, and editor in chief of the journal Vaccine. “I don’t like that there isn’t more data.”

The FDA should wait for the complete data.

[Doctor X]

The FDA should wait for the complete polls.

You are welcome.

– J.D.

[robinson]

ISRAEL

Vaccination starts
December 19, 2020, 07:24 GMT
Israel
Coronavirus Cases:
370,152
Deaths:
3,057

February 10, 2021, 05:42 GMT
Israel
Coronavirus Cases:
703,719
Deaths:
5,216

Herd immunity reached Jun 2021

June 10, 2021, 07:24 GMT
Israel
Coronavirus Cases:
839,585
Deaths:
6,418

February 10, 2022, 01:20 GMT
Israel
Coronavirus Cases:
3,316,235
Deaths:
9,337

[robinson]

In case you can't do maths, since herd immunity was reached, 2.5 million new cases

Almost all of them, including the serious ones, are vaccinated people

[Anaxagoras]

In case you can't do maths, since herd immunity was reached, 2.5 million new cases

Almost all of them, including the serious ones, are vaccinated people

Evidence?

June 10, 2021, 07:24 GMT
Israel
Coronavirus Cases:
839,585
Deaths:
6,418

February 10, 2022, 01:20 GMT
Israel
Coronavirus Cases:
3,316,235
Deaths:
9,337

So, up until June 10, 2021, 839,585 cases led to 6,418 deaths. That's a CFR of 0.76%.
Since June 10, 2021 until present, there have been 2,476,650 additional new cases and 2,919 additional deaths. That's a CFR of 0.12%.

The death rate per case is over six times lower than it had been before vaccines.

[robinson]

If the Covid mRNA treatment doesn’t stop infection or transmission

Then the definition of “work” is going to have to be changed

And the authorities actually changed the definition of "vaccine"

And the politicians and wealthy fucks (Fauci, Bill Gates etc.) are now saying they never claimed the mRNA vaccines would halt the spread, prevent infection, prevent you from getting sick, prevent you from experiencing death from Covid

But the useful idiots are still sucking that cock

[robinson]

The death rate per case is over six times lower than it had been before vaccines.

That is not accurate or true

[Anaxagoras]

The death rate per case is over six times lower than it had been before vaccines.

That is not accurate or true

It's just math. The difference between 0.76 and 0.12.

[Doctor X]

Numbers are liberal, Anax.

– J.D.

[robinson]

The death rate is how many people die over time.

It’s exactly like discussing the death rate on a highway. After improvements are made, if the Number of deadly accidents stays the same, And the number of accidents drastically increases, you don’t get the claim that the death rate went down

[robinson]

Well, you can, but it’s not accurate, and it’s wrong

[Pyrrho]

"Herd immunity" is a rather quaint notion in light of how often this virus mutates into new strains.

[robinson]

Israel’s Military Says it Has Reached Herd Immunity to COVID

Israel has reached herd immunity

[robinson]

Israel may have reached a ‘sort of herd immunity’ from COVID, expert says

Eran Segal says virus cases down 97% since January as result of successful vaccination drive, additional restrictions can safely be lifted

https://www.timesofisrael.com/israel-ma ... pert-says/

[Pyrrho]

At work we are required to reserve our desk for each day we're at the office, we're required to be vaccinated to go to the office, and we're required to wear a mask when we're in the office. There is a push for everyone to get back to working in the office. So various people are showing up at the office without following any of the rules, and "social distancing" is not done at all. Next week there will be meetings in closed conference rooms. I expect there will be several cases starting the first week of March...and there will be more meetings that week. To show that virus who is boss, I guess. I have no objection to working in the office. I do object to people acting as if COVID-19 is gone, baby, solid gone.

[robinson]

People are fucking idiots

[Doctor X]

"Herd immunity" is a rather quaint notion in light of how often this virus mutates into new strains.

To achieve herd immunity, you actually have to have people who are immune or, at the very least, unable to significantly suffer from the virus as well as, critically, transmit it.

I am unaware that that has happened with the vaccines, "natural immunity," or Camel Toe's cackles.








Let me rephrase that.

Nevertheless, since reality is not a "black or white" "MY WAY OR U FASCISTS!!" dichotomy, that does not mean:

• 1. Masks work.
  2. Lockdowns work.
  3. The vaccines are useless.
  4. The vaccines cause variants.
  5. Trump or Brandon are actually relevant.

https://i.imgur.com/tqWAAZi.png
We ALL Float Down Here, Shinji!

– J.D.

[robinson]

While researching this I found multiple experts who were trying to warn the world about how the vaccines were not going to work

[Pyrrho]

No point in "masking up" in a cubicle and then belly up to the shared chow line in a crowded meeting room to scarf down pizza and Diet Cokes. And any mask I wear at the office will be futile because nobody else will be wearing one, especially not the cardiac-disasters-in-the-making group of big eaters and jabbermouths my cubicle is next to. Rest assured I will have a bottle of good hand cleaner at my desk, and I'll keep my fingers out of my nose, like I was taught in kindergarten.

[Pyrrho]

https://www.npr.org/sections/goatsandso ... -infection

Abu-Raddad and his team have been tracking reinfections in Qatar for more than a year. In one study, the team analyzed about 1,300 reinfections among more than 350,000 people in Qatar. They found that a prior COVID-19 infection reduced the risk of hospitalization upon reinfection by about 90% compared with in people having their first infection.

These findings, published in the New England Journal of Medicine in December, are consistent with data released by the Centers for Disease Control and Prevention last month. In that study, a prior infection reduced the risk of hospitalization during the delta surge by more than 50 times compared with in people who hadn't had a prior infection and were not vaccinated. People who had had both a prior infection and were vaccinated had the most protection.

And here's the "really good news," Abu-Raddad says: This protection against severe disease persists, perhaps for years. "We've been following this same group of people for over a year and a half now, we don't see much waning. If it's there, it's too small to discern."

But the good news doesn't necessarily hold true for everyone. This long-term protection is seen in healthy people under age 50, Abu-Raddad points out.

NEJM:

https://www.nejm.org/doi/full/10.1056/NEJMc2108120

CDC:

https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e1.htm

[Pyrrho]

Also in NEJM is this article about the Merck pill for treatment of COVID-19 symptoms:

https://www.nejm.org/doi/full/10.1056/NEJMoa2116044

A total of 1433 participants underwent randomization; 716 were assigned to receive molnupiravir and 717 to receive placebo. With the exception of an imbalance in sex, baseline characteristics were similar in the two groups. The superiority of molnupiravir was demonstrated at the interim analysis; the risk of hospitalization for any cause or death through day 29 was lower with molnupiravir (28 of 385 participants [7.3%]) than with placebo (53 of 377 [14.1%]) (difference, −6.8 percentage points; 95% confidence interval [CI], −11.3 to −2.4; P=0.001).

[Pyrrho]

https://twitter.com/EricTopol/status/14 ... 1862237185

https://erictopol.substack.com/p/ground ... rior-covid

The CDC has been completely unwilling to recognize confirmed Prior Covid as equivalent to at least 1-dose or 2-doses of vaccines. While mandates worked to increase the number of people who got vaccinated in the United States, they have augmented the divisiveness among those with Prior Covid who rightfully believe they have immunity. The studies that I’ve reviewed all have the problem of survivor bias (i.e. people who died with Prior Covid, not studied), and the marked heterogeneity and durability of the immune response for the spectrum of symptoms (from none to severe). And there is the unpredictability of Covid. That vaccination provides some protection versus Long Covid, which is absent from infection. But what I am referring to here is that people who had prior Covid deserve respect for having a level of immunity that is at least comparable to vaccination and would certainly be enhanced with a dose of a vaccine.

...

Things have changed since the Omicron variant, with its extreme of immune evasion, became dominant in many countries throughout the world. Reinfection quickly spiked among people with prior Covid, when previously in the UK it was quite rare, not at least a 16-fold risk. The risk was further substantiated by the report from Qatar in this week’s NEJM that Prior Covid protection vs symptomatic reinfection was high, about 90% for prior variants, but dropped down to 56% with Omicron.

[Ben Trovado]

https://www.nytimes.com/2022/02/09/heal ... cines.html

The Food and Drug Administration’s upcoming review of the Pfizer-BioNTech coronavirus vaccine for young children is without precedent in recent history.

Next week, scientific advisers to the agency will decide whether to endorse two doses of the vaccine for children 6 months through 4 years of age, before clinical trials have shown the full course — three doses — to be effective. Such an authorization would be a first for the agency, many experts say.

In fact, interim results from the trial suggested that two doses of the vaccine did not produce a strong immune response in children aged 2 through 4. Results from trials of the third dose are expected in a few weeks.

...

But the agency’s review of incomplete data as a basis for authorization has alarmed some experts.

“We’ve never done that before, that’s what gives me some pause,” said Dr. Gregory Poland, founder and director of the Mayo Vaccine Research Group in Minnesota, and editor in chief of the journal Vaccine. “I don’t like that there isn’t more data.”

Jesus, yes.

Especially with the rates of serious cases being so low to begin with for anyone young, moving forward without full data is full blown crazy.


The FDA should wait for the complete data.

[Doctor X]

What pisses me off is that these rushes in the name of conformity actually give credence to the real anti-vax movement.

– J.D.

[robinson]

https://twitter.com/Raging_Red/status/1 ... _l9vPkinNQ

[Pyrrho]

https://www.science.org/doi/10.1126/science.abn2688

Specificity mapping of circulating B cells revealed that mRNA-1273 boost immunofocused ChAdOx1-primed responses onto epitopes expressed on prefusion-stabilized S. Monoclonal antibodies isolated from mRNA-1273 boosted participants displayed overall higher binding affinities and increased breadth of reactivity against VOCs relative to those isolated from ChAdOx1-boosted individuals. Overall, the results provide molecular insight into the enhanced quality of the B cell response induced following heterologous mRNA booster vaccination.